A Novel mechanism for depot-specific leptin gene expression regulation and its persistence after weight loss

This file was created by the TYPO3 extension publications --- Timezone: CEST Creation date: 2026-05-21 Creation time: 16:16:19 --- Number of references 64 article RN1485 A Novel mechanism for depot-specific leptin gene expression regulation and its persistence after weight loss Journal Article 2026 2589-0042 (Electronic) 2589-0042 (Linking) 10.1016/j.isci.2026.115101 iScience 29 115101 4 https://www.ncbi.nlm.nih.gov/pubmed/41907434 N. Taege J. H. Britsemmer A. Israel C. Krause S. Junge A. Feuchtinger S. Ussar P. T. Pfluger T. Gemoll S. C. Schriever H. Kirchner article RN1486 Epigenetic regulation in MASLD - insight for therapeutic target discovery Journal Article 2026 1750-192X (Electronic) 1750-192X (Linking) 10.1080/17501911.2026.2633978 Epigenomics 1-23 https://www.ncbi.nlm.nih.gov/pubmed/41738314 J. H. Britsemmer N. Lopez Alcantara H. Kirchner article RN1489 Pregnancy negates thyroid hormone-induced pyrexia Journal Article 2026 1522-1555 (Electronic) 0193-1849 (Linking) 10.1152/ajpendo.00569.2025 Am J Physiol Endocrinol Metab https://www.ncbi.nlm.nih.gov/pubmed/42090193 N. Lopez-Alcantara L. Adam J. Resch S. Keipert J. Mittag R. Oelkrug article RN1487 The timing of antenatal glucocorticoids determines the receptor sensitivity in preterm infants Journal Article 2026 1945-7197 (Electronic) 0021-972X (Linking) 10.1210/clinem/dgag066 J Clin Endocrinol Metab https://www.ncbi.nlm.nih.gov/pubmed/41693150 I. Fortmann J. H. Britsemmer M. Lehmann N. Taege H. Oster H. Kirchner C. Haertel M. Astiz article RN1488 Thyrotropin-releasing hormone neurons of different hypothalamic nuclei increase energy expenditure Journal Article 2026 2041-1723 (Electronic) 2041-1723 (Linking) 10.1038/s41467-026-71617-3 Nat Commun 17 1 https://www.ncbi.nlm.nih.gov/pubmed/41980928 A. Constantinescu A. Chandrasekar L. Kleindienst L. Hohne N. Da Silva Lima M. Richter V. Neve F. Spiecker I. Stolting W. Brandt U. Matschl J. Wenzel R. Oelkrug V. Prevot H. Heuer J. Mittag R. Nogueiras M. Schwaninger H. Muller-Fielitz article RN1481 Schilddrüsenhormone - Unterfunktion erkennen! Journal Article 2025 9 1 Deutsche Hebammenzeitschrift 77 https://staudeverlag.de/unterfunktion-erkennen/ 30-35 9 https://staudeverlag.de/unterfunktion-erkennen/ J. Mittag article RN1479 Dysregulation of hepatic deiodinase type I in metabolically associated steatotic liver disease Journal Article 2025 1479-6813 (Electronic) 0952-5041 (Linking) 10.1530/JME-25-0096 J Mol Endocrinol https://www.ncbi.nlm.nih.gov/pubmed/40736997 N. Lopez-Alcantara A. M. Naujack Y. Chen N. Taege C. Geissler R. Oelkrug E. K. Wirth L. Schomburg A. Boelen H. Kirchner J. Mittag article RN1468 Hypothalamic control of heart rate and body temperature by thyroid hormones Journal Article 2025 1573-2606 (Electronic) 1389-9155 (Linking) 10.1007/s11154-025-09966-5 Rev Endocr Metab Disord https://www.ncbi.nlm.nih.gov/pubmed/40244498 J. Mittag B. Kolms article RN1467 Impaired thyroid hormone receptor signaling in anterior hypothalamic parvalbumin neurons causes bradycardia in male mice Journal Article 2025 2235-0802 (Electronic) 2235-0640 (Print) 2235-0640 (Linking) 10.1530/ETJ-25-0055 Eur Thyroid J 14 3 https://www.ncbi.nlm.nih.gov/pubmed/40334052 B. Kolms R. Dore S. C. Sentis L. V. M. Assis H. Oster J. Mittag article RN1466 JNK1 in SF1 neurons regulates the central action of thyroid hormones on hepatic lipid metabolism Journal Article 2025 2212-8778 (Electronic) 2212-8778 (Linking) 10.1016/j.molmet.2025.102170 Mol Metab 102170 https://www.ncbi.nlm.nih.gov/pubmed/40419019 I. Fernandez-Gonzalez O. Freire-Agulleiro V. Ferreira M. Silveira-Loureiro E. Rial-Pensado P. Garrido-Gil G. Martinez P. Rada J. L. Labandeira-Garcia J. Mittag I. Gonzalez-Garcia C. Dieguez R. Nogueiras A. M. Valverde R. J. Davis G. Sabio O. Barca-Mayo M. Lopez article RN1449 Sex-specific role of epigenetic modification of a leptin upstream enhancer in adipose tissue Journal Article 2025 1868-7083 (Electronic) 1868-7075 (Linking) 10.1186/s13148-025-01830-2 Clin Epigenetics 17 21 1 https://www.ncbi.nlm.nih.gov/pubmed/39934931 L. Muller R. Oelkrug J. Mittag A. Hoffmann A. Ghosh F. Noe C. Wolfrum E. Guiu Jurado N. Kloting A. Dietrich M. Blüher P. Kovacs K. Krause M. Keller article RN1424 Canonical and noncanonical contribution of thyroid hormone receptor isoforms alpha and beta to cardiac hypertrophy and heart rate in male mice Journal Article 2024 1557-9077 (Electronic) 1050-7256 (Linking) 10.1089/thy.2023.0683 Thyroid https://www.ncbi.nlm.nih.gov/pubmed/38757582 D. Geist G. S. Hones S. C. Grund J. Pape D. Siemes P. Spangenberg E. Tolstik S. Dorr N. Spielmann H. Fuchs V. Gailus-Durner M. Angelis J. Mittag D. R. Engel D. Fuhrer K. Lorenz L. C. Moeller article RN1416 Cardiac recovery from pressure overload is not altered by thyroid hormone status in old mice Journal Article 2024 1664-2392 (Print) 1664-2392 (Electronic) 1664-2392 (Linking) 10.3389/fendo.2024.1339741 Front Endocrinol (Lausanne) 15 1339741 https://www.ncbi.nlm.nih.gov/pubmed/38455657 H. Kerp J. Gassen S. C. Grund G. S. Hones S. Dorr J. Mittag N. Harting F. Kaiser L. C. Moeller K. Lorenz D. Fuhrer article RN1426 Epigenetic regulation of thyroid hormone action in human metabolic dysfunction associated steatohepatitis Journal Article 2024 2235-0802 (Electronic) 2235-0640 (Linking) 10.1530/ETJ-24-0080 Eur Thyroid J https://www.ncbi.nlm.nih.gov/pubmed/39189972 A. M. Naujack C. Krause J. H. Britsemmer N. Taege J. Mittag H. Kirchner article RN1415 Hypothalamic Thyroid Hormone Receptor alpha1 Signaling Controls Body Temperature Journal Article 2024 1557-9077 (Electronic) 1050-7256 (Linking) 10.1089/thy.2023.0513 Thyroid https://www.ncbi.nlm.nih.gov/pubmed/38149585 S. C. Sentis R. Dore R. Oelkrug B. Kolms K. A. Iwen J. Mittag article RN1427 Inhibition of Thyroid Hormone Signaling in the Zona Incerta Alters Basal Metabolic Rate, Behavior and Serum Glucocorticoids in Male Mice Journal Article 2024 1557-9077 (Electronic) 1050-7256 (Linking) 10.1089/thy.2024.0209 Thyroid https://www.ncbi.nlm.nih.gov/pubmed/39189416 J. Maier R. Dore R. Oelkrug A. Glatzel A. L. Cremer S. Binder M. Schwaninger H. Oster H. Backes J. Mittag article RN1417 Partial resistance to thyroid hormone-induced tachycardia and cardiac hypertrophy in mice lacking thyroid hormone receptor beta Journal Article 2024 1557-9077 (Electronic) 1050-7256 (Linking) 10.1089/thy.2023.0638 Thyroid https://www.ncbi.nlm.nih.gov/pubmed/38526409 R. Dore S. C. Sentis K. Johann N. Lopez Alcantara J. Resch A. Chandrasekar H. Muller-Fielitz L. C. Moeller D. Fuhrer M. Schwaninger B. Obermayer R. Opitz J. Mittag article RN1429 Serum CD5L as potential biomarker of thyroid hormone status during pregnancy Journal Article 2024 1872-8081 (Electronic) 0951-6433 (Linking) 10.1002/biof.2123 Biofactors https://www.ncbi.nlm.nih.gov/pubmed/39345206 S. Asaad T. S. Chillon D. Filipowicz B. Wilms F. Strenge E. Szczepanek-Parulska W. B. Minich S. M. Meyhofer J. U. Marquardt J. Mittag H. Oster M. Ruchala L. Schomburg article RN1480 Thyroid hormone receptor beta (THRB) dependent regulation of diurnal hepatic lipid metabolism in adult male mice Journal Article 2024 2948-2828 (Electronic) 2948-2828 (Linking) 10.1038/s44324-024-00023-4 NPJ Metab Health Dis 2 21 1 https://www.ncbi.nlm.nih.gov/pubmed/40603776 L. V. M. Assis L. Harder J. Inderhees O. Johren J. Mittag H. Oster article RN1428 Thyroid Hormone Receptors in Control of Heart Rate Journal Article 2024 1945-7170 (Electronic) 0013-7227 (Linking) 10.1210/endocr/bqae093 Endocrinology 165 9 https://www.ncbi.nlm.nih.gov/pubmed/39047059 R. Dore J. Mittag article RN1430 Thyroid hormones are required for thermogenesis of beige adipocytes induced by Zfp423 inactivation Journal Article 2024 2211-1247 (Electronic) 10.1016/j.celrep.2024.114987 Cell Rep 43 114987 12 https://www.ncbi.nlm.nih.gov/pubmed/39580797 L. Roth A. Hoffmann T. Hagemann L. Wagner C. Strehlau B. Sheikh L. Donndorf A. Ghosh F. Noe C. Wolfrum K. Krohn J. Weiner J. T. Heiker N. Kloting M. Stumvoll A. Tönjes M. Blüher J. Mittag K. Krause article RN1414 Tuning of liver circadian transcriptome rhythms by thyroid hormone state in male mice Journal Article 2024 2045-2322 (Electronic) 2045-2322 (Linking) 10.1038/s41598-023-50374-z Sci Rep 14 640 1 https://www.ncbi.nlm.nih.gov/pubmed/38182610 L. V. M. Assis L. Harder J. T. Lacerda R. Parsons M. Kaehler I. Cascorbi I. Nagel O. Rawashdeh J. Mittag H. Oster article RN1412 Lack of thyroid hormone receptor beta is not detrimental for non-alcoholic steatohepatitis progression Journal Article 2023 2589-0042 (Electronic) 2589-0042 (Linking) 10.1016/j.isci.2023.108064 iScience 26 108064 10 https://www.ncbi.nlm.nih.gov/pubmed/37822510 N. Lopez-Alcantara R. Oelkrug S. C. Sentis H. Kirchner J. Mittag article RN1411 Maternal thyroid hormone receptor beta activation in mice sparks brown fat thermogenesis in the offspring Journal Article 2023 2041-1723 (Electronic) 2041-1723 (Linking) 10.1038/s41467-023-42425-w Nat Commun 14 6742 1 https://www.ncbi.nlm.nih.gov/pubmed/37875497 R. Oelkrug L. Harder M. Pedaran A. Hoffmann B. Kolms J. Inderhees S. Gachkar J. Resch K. Johann O. Johren K. Krause J. Mittag article RN1397 Resistance to thyroid hormone induced tachycardia in RTHalpha syndrome Journal Article 2023 2041-1723 (Electronic) 2041-1723 (Linking) 10.1038/s41467-023-38960-1 Nat Commun 14 3312 1 https://www.ncbi.nlm.nih.gov/pubmed/37286550 R. Dore L. Watson S. Hollidge C. Krause S. C. Sentis R. Oelkrug C. Geissler K. Johann M. Pedaran G. Lyons N. Lopez-Alcantara J. Resch F. Sayk K. A. Iwen A. Franke T. J. Boysen J. W. Dalley K. Lorenz C. Moran K. L. Rennie A. Arner H. Kirchner K. Chatterjee J. Mittag article RN1367 Single-cell RNA-based phenotyping reveals a pivotal role of thyroid hormone receptor alpha for hypothalamic development Journal Article 2023 1477-9129 (Electronic) 0950-1991 (Linking) 10.1242/dev.201228 Development 150 3 https://www.ncbi.nlm.nih.gov/pubmed/36715020 V. K. A. Sreenivasan R. Dore J. Resch J. Maier C. Dietrich J. Henck S. Balachandran J. Mittag M. Spielmann article RN1368 Thyroid hormones regulate Zfp423 expression in regionally distinct adipose depots through direct and cell-autonomous action Journal Article 2023 2211-1247 (Electronic) 10.1016/j.celrep.2023.112088 Cell Rep 42 112088 2 https://www.ncbi.nlm.nih.gov/pubmed/36753417 L. Roth K. Johann G. S. Hones R. Oelkrug L. Wagner A. Hoffmann K. Krohn L. C. Moeller J. Weiner J. T. Heiker N. Kloting A. Tönjes M. Stumvoll M. Blüher J. Mittag K. Krause article RN1335 Gene therapy targeting the blood-brain barrier improves neurological symptoms in a model of genetic MCT8 deficiency Journal Article 2022 1460-2156 (Electronic) 0006-8950 (Linking) 10.1093/brain/awac243 Brain https://www.ncbi.nlm.nih.gov/pubmed/35929549 S. M. Sundaram A. Arrulo Pereira H. Muller-Fielitz H. Kopke M. De Angelis T. D. Muller H. Heuer J. Korbelin M. Krohn J. Mittag R. Nogueiras V. Prevot M. Schwaninger article RN1328 Rewiring of liver diurnal transcriptome rhythms by triiodothyronine (T3) supplementation Journal Article 2022 2050-084X (Electronic) 2050-084X (Linking) 10.7554/eLife.79405 Elife 11 https://www.ncbi.nlm.nih.gov/pubmed/35894384 L. V. M. Assis L. Harder J. T. Lacerda R. Parsons M. Kaehler I. Cascorbi I. Nagel O. Rawashdeh J. Mittag H. Oster article RN1366 Temperature modulates systemic and central actions of thyroid hormones on BAT thermogenesis Journal Article 2022 1664-042X (Print) 1664-042X (Electronic) 1664-042X (Linking) 10.3389/fphys.2022.1017381 Front Physiol 13 1017381 https://www.ncbi.nlm.nih.gov/pubmed/36467699 E. Rial-Pensado V. Rivas-Limeres C. Grijota-Martinez A. Rodriguez-Diaz V. Capelli O. Barca-Mayo R. Nogueiras J. Mittag C. Dieguez M. Lopez article RN1295 Too much too soon - Tissue-specific inactivation of deiodinase type 3 prematurely exposes brown fat to thyroid hormone Journal Article 2022 1945-7170 (Electronic) 0013-7227 (Linking) 10.1210/endocr/bqac032 Endocrinology https://www.ncbi.nlm.nih.gov/pubmed/35294005 R. Oelkrug J. Mittag article RN1327 TRalpha2-An Untuned Second Fiddle or Fine-Tuning Thyroid Hormone Action? Journal Article 2022 1422-0067 (Electronic) 1422-0067 (Linking) 10.3390/ijms23136998 Int J Mol Sci 23 13 https://www.ncbi.nlm.nih.gov/pubmed/35806002 G. S. Hones N. Harting J. Mittag F. J. Kaiser article RN26 An improved method for the precise unravelment of non-shivering brown fat thermokinetics Journal Article 2021 2045-2322 (Electronic) 2045-2322 (Linking) 10.1038/s41598-021-84200-1 Sci Rep 11 4799 1 https://www.ncbi.nlm.nih.gov/pubmed/33637831 R. Oelkrug J. Mittag article RN31 Determination of 3-iodothyronamine (3-T1AM) in mouse liver using liquid chromatography-tandem mass spectrometry Journal Article 2021 1873-376X (Electronic) 1570-0232 (Linking) 10.1016/j.jchromb.2021.122553 J Chromatogr B Analyt Technol Biomed Life Sci 1165 122553 https://www.ncbi.nlm.nih.gov/pubmed/33503577 Z. M. Li M. Miller S. Gachkar J. Mittag S. C. Schriever P. T. Pfluger K. W. Schramm M. De Angelis article RN2 Leptin counteracts hypothermia in hypothyroidism through its pyrexic effects and by stabilizing serum thyroid hormone levels Journal Article 2021 2212-8778 (Electronic) 2212-8778 (Linking) 10.1016/j.molmet.2021.101348 Mol Metab 54 101348 https://www.ncbi.nlm.nih.gov/pubmed/34610354 J. Weiner L. Roth M. Kranz P. Brust A. Boelen N. Kloting J. T. Heiker M. Blüher A. Tönjes P. T. Pfluger M. Stumvoll J. Mittag K. Krause article RN91 Maternal thyroid hormone programs cardiovascular functions in the offspring Journal Article 2021 1557-9077 (Electronic) 1050-7256 (Linking) 10.1089/thy.2021.0275 Thyroid https://www.ncbi.nlm.nih.gov/pubmed/34269617 M. Pedaran R. Oelkrug Q. Sun J. Resch L. Schomburg J. Mittag article RN1285 Orally Induced Hyperthyroidism Regulates Hypothalamic AMP-Activated Protein Kinase Journal Article 2021 2072-6643 (Electronic) 2072-6643 (Linking) 10.3390/nu13124204 Nutrients 13 12 https://www.ncbi.nlm.nih.gov/pubmed/34959756 V. Capelli C. Grijota-Martinez N. R. V. Dragano E. Rial-Pensado J. Ferno R. Nogueiras J. Mittag C. Dieguez M. Lopez article RN2 Small extracellular vesicle-mediated targeting of hypothalamic AMPKalpha1 corrects obesity through BAT activation Journal Article 2021 2522-5812 (Electronic) 2522-5812 (Linking) 10.1038/s42255-021-00467-8 Nat Metab 3 1415-1431 10 https://www.ncbi.nlm.nih.gov/pubmed/34675439 E. Milbank N. R. V. Dragano I. Gonzalez-Garcia M. R. Garcia V. Rivas-Limeres L. Perdomo G. Hilairet F. Ruiz-Pino P. Mallegol D. A. Morgan R. Iglesias-Rey C. Contreras L. Vergori J. Cunarro B. Porteiro A. Gavalda-Navarro R. Oelkrug A. Vidal J. Roa T. Sobrino F. Villarroya C. Dieguez R. Nogueiras C. Garcia-Caceres M. Tena-Sempere J. Mittag M. Carmen Martinez K. Rahmouni R. Andriantsitohaina M. Lopez article RN28 Thyroid hormones in the regulation of brown adipose tissue thermogenesis Journal Article 2021 2049-3614 (Print) 2049-3614 (Linking) 10.1530/EC-20-0562 Endocr Connect 10 R106-R115 2 https://www.ncbi.nlm.nih.gov/pubmed/33491659 S. C. Sentis R. Oelkrug J. Mittag article RN90 Thyroid wars: the rise of central actions Journal Article 2021 1879-3061 (Electronic) 1043-2760 (Linking) 10.1016/j.tem.2021.05.006 Trends Endocrinol Metab https://www.ncbi.nlm.nih.gov/pubmed/34294513 V. Capelli C. Dieguez J. Mittag M. Lopez article RN6 CD5L Constitutes a Novel Biomarker for Integrated Hepatic Thyroid Hormone Action Journal Article 2020 1557-9077 (Electronic) 1050-7256 (Linking) 10.1089/thy.2019.0635 Thyroid 30 908-923 6 https://www.ncbi.nlm.nih.gov/pubmed/32183611 S. Nock K. Johann L. Harder E. K. Wirth K. Renko C. S. Hoefig V. Kracke J. Hackler B. Engelmann M. Rauner J. Kohrle L. Schomburg G. Homuth U. Volker G. Brabant J. Mittag article RN1 Central Hypothyroidism Impairs Heart Rate Stability and Prevents Thyroid Hormone-Induced Cardiac Hypertrophy and Pyrexia Journal Article 2020 1557-9077 (Electronic) 1050-7256 (Linking) 10.1089/thy.2019.0705 Thyroid https://www.ncbi.nlm.nih.gov/pubmed/32188347 B. Herrmann L. Harder R. Oelkrug J. Chen S. Gachkar S. Nock J. Resch M. Korkowski H. Heuer J. Mittag article RN25 Cross-sectional analysis of trace element status in thyroid disease Journal Article 2020 1878-3252 (Electronic) 0946-672X (Linking) 10.1016/j.jtemb.2019.126430 J Trace Elem Med Biol 58 126430 https://www.ncbi.nlm.nih.gov/pubmed/31835129 S. Mehl Q. Sun C. L. Gorlich J. Hackler J. F. Kopp K. Renko J. Mittag T. Schwerdtle L. Schomburg article RN29 Dopamine receptor D1- and D2-agonists do not spark brown adipose tissue thermogenesis in mice Journal Article 2020 2045-2322 (Electronic) 2045-2322 (Linking) 10.1038/s41598-020-77143-6 Sci Rep 10 20203 1 https://www.ncbi.nlm.nih.gov/pubmed/33214601 F. M. Raffaelli J. Resch R. Oelkrug K. A. Iwen J. Mittag article RN30 Maternal Brown Fat Thermogenesis Programs Glucose Tolerance in the Male Offspring Journal Article 2020 2211-1247 (Electronic) 10.1016/j.celrep.2020.108351 Cell Rep 33 108351 5 https://www.ncbi.nlm.nih.gov/pubmed/33147454 R. Oelkrug C. Krause B. Herrmann J. Resch S. Gachkar A. T. El Gammal S. Wolter O. Mann H. Oster H. Kirchner J. Mittag article RN4 More Than Fever - Novel Concepts in the Regulation of Body Temperature by Thyroid Hormones Journal Article 2020 1439-3646 (Electronic) 0947-7349 (Linking) 10.1055/a-1014-2510 Exp Clin Endocrinol Diabetes 128 428-431 6-07 https://www.ncbi.nlm.nih.gov/pubmed/31652476 J. Mittag article RN8 N- and O-Acetylated 3-Iodothyronamines Have No Metabolic or Thermogenic Effects in Male Mice Journal Article 2020 2235-0640 (Print) 2235-0640 (Linking) 10.1159/000504887 Eur Thyroid J 9 57-66 2 https://www.ncbi.nlm.nih.gov/pubmed/32257954 S. Gachkar R. Oelkrug B. Herrmann T. S. Scanlan Q. Sun H. Biebermann C. S. Hoefig L. Schomburg J. Mittag article RN24 Nesfatin-1 decreases the motivational and rewarding value of food Journal Article 2020 1740-634X (Electronic) 0893-133X (Linking) 10.1038/s41386-020-0682-3 Neuropsychopharmacology https://www.ncbi.nlm.nih.gov/pubmed/32353862 R. Dore R. Krotenko J. P. Reising L. Murru S. M. Sundaram A. Di Spiezio H. Muller-Fielitz M. Schwaninger O. Johren J. Mittag M. Passafaro M. Shanabrough T. L. Horvath A.S. Schulz H. Lehnert article RN5 Unraveling the Molecular Basis for Successful Thyroid Hormone Replacement Therapy: The Need for New Thyroid Tissue- and Pathway-Specific Biomarkers Journal Article 2020 1439-3646 (Electronic) 0947-7349 (Linking) 10.1055/a-1012-8484 Exp Clin Endocrinol Diabetes 128 473-478 6-07 https://www.ncbi.nlm.nih.gov/pubmed/31590191 S. Nock C. Hofig L. Harder L. Schomburg G. Brabant J. Mittag article RN7 Aortic Effects of Thyroid Hormone in Male Mice Journal Article 2019 1479-6813 (Electronic) 0952-5041 (Linking) 10.1530/JME-18-0217 J Mol Endocrinol http://www.ncbi.nlm.nih.gov/pubmed/30608905 S. Gachkar S. Nock C. Geissler R. Olkrug K. Johann J. Resch A. Rahman A. Arner H. Kirchner J. Mittag article RN2 Thyroid-Hormone-Induced Browning of White Adipose Tissue Does Not Contribute to Thermogenesis and Glucose Consumption Journal Article 2019 2211-1247 (Electronic) 10.1016/j.celrep.2019.05.054 Cell Rep 27 3385-3400 e3 11 http://www.ncbi.nlm.nih.gov/pubmed/31189119 K. Johann A. L. Cremer A. W. Fischer M. Heine E. R. Pensado J. Resch S. Nock S. Virtue L. Harder R. Oelkrug M. Astiz G. Brabant A. Warner A. Vidal-Puig H. Oster A. Boelen M. Lopez J. Heeren J. W. Dalley H. Backes J. Mittag article RN20 3-Iodothyronamine Activates a Set of Membrane Proteins in Murine Hypothalamic Cell Lines Journal Article 2018 1664-2392 (Print) 1664-2392 (Linking) 10.3389/fendo.2018.00523 Front Endocrinol (Lausanne) 9 523 http://www.ncbi.nlm.nih.gov/pubmed/30298050 J. Braunig S. Mergler S. Jyrch C. S. Hoefig M. Rosowski J. Mittag H. Biebermann N. Khajavi article RN22 Effects of sildenafil treatment on thermogenesis and glucose homeostasis in diet-induced obese mice Journal Article 2018 2044-4052 (Electronic) 2044-4052 (Linking) 10.1038/s41387-018-0026-0 Nutr Diabetes 8 9 1 http://www.ncbi.nlm.nih.gov/pubmed/29549244 K. Johann M. C. Reis L. Harder B. Herrmann S. Gachkar J. Mittag R. Oelkrug article RN11 In vivo Effects of Repeated Thyronamine Administration in Male C57BL/6J Mice Journal Article 2018 2235-0640 (Print) 2235-0640 (Linking) 10.1159/000481856 Eur Thyroid J 7 3-12 1 http://www.ncbi.nlm.nih.gov/pubmed/29594048 L. Harder N. Schanze A. Sarsenbayeva F. Kugel J. Kohrle L. Schomburg J. Mittag C. S. Hoefig article RN21 Low-level mitochondrial heteroplasmy modulates DNA replication, glucose metabolism and lifespan in mice Journal Article 2018 2045-2322 (Electronic) 2045-2322 (Linking) 10.1038/s41598-018-24290-6 Sci Rep 8 5872 1 http://www.ncbi.nlm.nih.gov/pubmed/29651131 M. Hirose P. Schilf Y. Gupta K. Zarse A. Kunstner A. Fahnrich H. Busch J. Yin M. N. Wright A. Ziegler M. Vallier M. Belheouane J. F. Baines D. Tautz K. Johann R. Oelkrug J. Mittag H. Lehnert A. Othman O. Johren M. Schwaninger C. Prehn J. Adamski K. Shima J. Rupp R. Hasler G. Fuellen R. Kohling M. Ristow S. M. Ibrahim article RN10 Maternal thyroid hormone is required for parvalbumin neurone development in the anterior hypothalamic area Journal Article 2018 1365-2826 (Electronic) 0953-8194 (Linking) 10.1111/jne.12573 J Neuroendocrinol 30 e12573 3 http://www.ncbi.nlm.nih.gov/pubmed/29377458 L. Harder S. Dudazy-Gralla H. Muller-Fielitz J. Hjerling Leffler B. Vennstrom H. Heuer J. Mittag article RN23 Reduced expression of thyroid hormone receptor beta in human nonalcoholic steatohepatitis Journal Article 2018 2049-3614 (Print) 2049-3614 (Linking) 10.1530/EC-18-0499 Endocr Connect http://www.ncbi.nlm.nih.gov/pubmed/30496129 C. Krause M. Grohs A. El Gammal S. Wolter H. Lehnert O. Mann J. Mittag H. Kirchner article RN19 The Trace Amine-Associated Receptor 1 Agonist 3-Iodothyronamine Induces Biased Signaling at the Serotonin 1b Receptor Journal Article 2018 1663-9812 (Print) 1663-9812 (Linking) 10.3389/fphar.2018.00222 Front Pharmacol 9 222 http://www.ncbi.nlm.nih.gov/pubmed/29593543 J. Braunig J. Dinter C. S. Hofig S. Paisdzior M. Szczepek P. Scheerer M. Rosowski J. Mittag G. Kleinau H. Biebermann article RN18 3-Iodothyronamine Decreases Expression of Genes Involved in Iodide Metabolism in Mouse Thyroids and Inhibits Iodide Uptake in PCCL3 Thyrocytes Journal Article 2017 1557-9077 (Electronic) 1050-7256 (Linking) 10.1089/thy.2016.0182 Thyroid 27 11-22 1 http://www.ncbi.nlm.nih.gov/pubmed/27788620 N. Schanze S. F. Jacobi E. Rijntjes S. Mergler M. Del Olmo C. S. Hoefig N. Khajavi I. Lehmphul H. Biebermann J. Mittag J. Kohrle article RN9 3-Iodothyronamine Induces Tail Vasodilation Through Central Action in Male Mice Journal Article 2017 1945-7170 (Electronic) 0013-7227 (Linking) 10.1210/en.2016-1951 Endocrinology 158 1977-1984 6 http://www.ncbi.nlm.nih.gov/pubmed/28368510 S. Gachkar R. Oelkrug N. Martinez-Sanchez E. Rial-Pensado A. Warner C. S. Hoefig M. Lopez J. Mittag article RN13 Dwarfism and insulin resistance in male offspring caused by alpha1-adrenergic antagonism during pregnancy Journal Article 2017 2212-8778 (Electronic) 2212-8778 (Linking) 10.1016/j.molmet.2017.06.016 Mol Metab 6 1126-1136 10 http://www.ncbi.nlm.nih.gov/pubmed/29031714 R. Oelkrug B. Herrmann C. Geissler L. Harder C. Koch H. Lehnert H. Oster H. Kirchner J. Mittag article RN16 Hypothalamic AMPK-ER Stress-JNK1 Axis Mediates the Central Actions of Thyroid Hormones on Energy Balance Journal Article 2017 1932-7420 (Electronic) 1550-4131 (Linking) 10.1016/j.cmet.2017.06.014 Cell Metab 26 212-229 e12 1 http://www.ncbi.nlm.nih.gov/pubmed/28683288 N. Martinez-Sanchez P. Seoane-Collazo C. Contreras L. Varela J. Villarroya E. Rial-Pensado X. Buque I. Aurrekoetxea T. C. Delgado R. Vazquez-Martinez I. Gonzalez-Garcia J. Roa A. J. Whittle B. Gomez-Santos V. Velagapudi Y. C. L. Tung D. A. Morgan P. J. Voshol P. B. Morentin T. Lopez-Gonzalez L. Linares-Pose F. Gonzalez K. Chatterjee T. Sobrino G. Medina-Gomez R. J. Davis N. Casals M. Oresic A. P. Coll A. Vidal-Puig J. Mittag M. Tena-Sempere M. M. Malagon C. Dieguez M. L. Martinez-Chantar P. Aspichueta K. Rahmouni R. Nogueiras G. Sabio F. Villarroya M. Lopez article RN17 Tanycytes control the hormonal output of the hypothalamic-pituitary-thyroid axis Journal Article 2017 2041-1723 (Electronic) 2041-1723 (Linking) 10.1038/s41467-017-00604-6 Nat Commun 8 484 1 http://www.ncbi.nlm.nih.gov/pubmed/28883467 H. Muller-Fielitz M. Stahr M. Bernau M. Richter S. Abele V. Krajka A. Benzin J. Wenzel K. Kalies J. Mittag H. Heuer S. Offermanns M. Schwaninger article RN14 The thermogenic effect of nesfatin-1 requires recruitment of the melanocortin system Journal Article 2017 1479-6805 (Electronic) 0022-0795 (Linking) 10.1530/JOE-17-0151 J Endocrinol 235 111-122 2 http://www.ncbi.nlm.nih.gov/pubmed/28851749 R. Dore L. Levata S. Gachkar O. Johren J. Mittag H. Lehnert A.S. Schulz